BDBM50240184 CHEMBL4066371::US9962398, Compound MST-134

SMILES NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(Cl)cc2F)cc1

InChI Key InChIKey=ILLWLWJTNFHQRA-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50240184   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240184(CHEMBL4066371 | US9962398, Compound MST-134)
Affinity DataKi:  5.10nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240184(CHEMBL4066371 | US9962398, Compound MST-134)
Affinity DataKi:  5.10nMAssay Description:Inhibitory activity against dog gastric proton-pump enzyme H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50240184(CHEMBL4066371 | US9962398, Compound MST-134)
Affinity DataKi:  7.90nMAssay Description:The compound was tested in vivo for inhibition of gastric proton-pump enzyme H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50240184(CHEMBL4066371 | US9962398, Compound MST-134)
Affinity DataKi:  7.90nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240184(CHEMBL4066371 | US9962398, Compound MST-134)
Affinity DataKi:  162nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240184(CHEMBL4066371 | US9962398, Compound MST-134)
Affinity DataKi:  162nMAssay Description:Inhibitory activity against dog gastric proton-pump enzyme H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240184(CHEMBL4066371 | US9962398, Compound MST-134)
Affinity DataKi:  436nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240184(CHEMBL4066371 | US9962398, Compound MST-134)
Affinity DataKi:  436nMAssay Description:Inhibitory activity of gastric proton-pump enzyme H+/K+ ATPase was determined at 50 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed