BDBM50240404 (Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3-yl)-2-methyl-propan-1-one::1-(2-isopropylH-pyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one::CHEMBL19449::IBUDILAST

SMILES: CC(C)c1c(c2ccccn2n1)C(=O)C(C)C

InChI Key: InChIKey=ZJVFLBOZORBYFE-UHFFFAOYSA-N

Data: 1 KI  12 IC50  1 Kd  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50240404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	239	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	166	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.99E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	239	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	166	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Human)	BDBM50240404 (CHEMBL19449 | (Ibudilast)1-(2-Isopropyl-pyrazolo[1...) Show SMILES Show InChI	GoogleScholar	UniChem		3.09E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair