BDBM50240612 CHEMBL306946::GNF-PF-2691::Indolo[2,1-b]quinazoline-6,12-dione::TCMDC-125859::TRYPTANTHRIN::US10669273, Compound 5a

SMILES: O=C1c2ccccc2-n2c1nc1ccccc1c2=O

InChI Key: InChIKey=VQQVWGVXDIPORV-UHFFFAOYSA-N

Data: 3 KI  16 IC50  3 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50240612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Indoleamine 2,3-dioxygenase 2 (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 2 (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Prostaglandin G/H synthase 2 (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	194	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.99E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		581	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		4.81E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 2 (Human)	BDBM50240612 (CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...) Show SMILES Show InChI	GoogleScholar	UniChem		1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair