BDBM50240701 2-Methyl-10-piperazin-1-yl-4H-3-thia-4,9-diaza-benzo[f]azulene::4-Desmethylolanzapine::CHEMBL1125::desmethylolanzapine::olanzapine, N-desmethyl

SMILES: Cc1cc2c(Nc3ccccc3N=C2N2CCNCC2)s1

InChI Key: InChIKey=FHPIXVHJEIZKJW-UHFFFAOYSA-N

Data: 10 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50240701   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serotonin 2 (5-HT2) receptor (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		203	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		333	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1/Beta-2/Beta-3 adrenergic receptor (Human)	BDBM50240701 (CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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