BDBM50240709 (R)-4'-(3-(3-(dimethylamino)pyrrolidin-1-yl)propoxy)biphenyl-4-carbonitrile::4'-[3-((R)-3-Dimethylamino-pyrrolidin-1-yl)-propoxy]-biphenyl-4-carbonitrile::A-331440::CHEMBL319000

SMILES: CN(C)[C@@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C#N)C1

InChI Key: InChIKey=FXIPXWLVYIHFEP-UHFFFAOYSA-N

Data: 12 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50240709   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Human)	BDBM50240709 (A-331440 | 4'-[3-((R)-3-Dimethylamino-pyrrolidin-1...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50240709 (A-331440 | 4'-[3-((R)-3-Dimethylamino-pyrrolidin-1...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50240709 (A-331440 | 4'-[3-((R)-3-Dimethylamino-pyrrolidin-1...) Show SMILES Show InChI	GoogleScholar	UniChem		3.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50240709 (A-331440 | 4'-[3-((R)-3-Dimethylamino-pyrrolidin-1...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Hrh3 protein (Rat)	BDBM50240709 (A-331440 | 4'-[3-((R)-3-Dimethylamino-pyrrolidin-1...) Show SMILES Show InChI	GoogleScholar	UniChem		6.28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Rat)	BDBM50240709 (A-331440 | 4'-[3-((R)-3-Dimethylamino-pyrrolidin-1...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Hrh3 protein (Rat)	BDBM50240709 (A-331440 | 4'-[3-((R)-3-Dimethylamino-pyrrolidin-1...) Show SMILES Show InChI	GoogleScholar	UniChem		21.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50240709 (A-331440 | 4'-[3-((R)-3-Dimethylamino-pyrrolidin-1...) Show SMILES Show InChI	GoogleScholar	UniChem		22.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50240709 (A-331440 | 4'-[3-((R)-3-Dimethylamino-pyrrolidin-1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H2 receptor (Human)	BDBM50240709 (A-331440 | 4'-[3-((R)-3-Dimethylamino-pyrrolidin-1...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H4 receptor (Human)	BDBM50240709 (A-331440 | 4'-[3-((R)-3-Dimethylamino-pyrrolidin-1...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H2 receptor (Human)	BDBM50240709 (A-331440 | 4'-[3-((R)-3-Dimethylamino-pyrrolidin-1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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