BDBM50240886 CHEMBL4077717
SMILES Cc1cccc(COc2cc(=O)n3[C@H](Cc4ccccc4)COCc3n2)n1
InChI Key InChIKey=YNSSLYBREVKLTK-GOSISDBHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50240886
Affinity DataKi: 16nMAssay Description:Displacement of [3H]MPEPy from human mGlu5 expressed in HEK293FT cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Negative allosteric modulation of rat mGlu5 expressed in HEK293 cells assessed as inhibition of glutamate-induced intracellular calcium accumulation ...More data for this Ligand-Target Pair