BDBM50241029 1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol::CHEMBL383322::R 848::R-848::Resiquimod::US10457681, Compound Resiquimod::US10487084, Compound Resiquimod::US10508115, Compound Resiquimod::US10919895, Resiquimod::US10981914, Compound Resiquimod::US9334268, resiquimod

SMILES: CCOCc1nc2c(n1CC(C)(C)O)c3ccccc3nc2N

InChI Key: InChIKey=BXNMTOQRYBFHNZ-UHFFFAOYSA-N

Data: 1 IC50  32 EC50

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50241029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	363	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	616	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	760	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.13E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.87E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a
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Oxidized purine nucleoside triphosphate hydrolase (Human)	BDBM50241029 (1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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