BDBM50241089 2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoethyl)-1H-pyrazol-3-ylamino)quinazolin-7-yloxy)propyl)amino)ethyl dihydrogen phosphate::2-ethyl3-4-5-2-3-fluorophenylamino)-2-oxoethyl)-1H-pyrazol-3-ylamino)quinazolin-7-yloxy)propyl)amino)ethyl dihydrogen phosphate::AZD1152, 33::CHEMBL415049

SMILES: CCN(CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1)CCOP(O)(O)=O

InChI Key: InChIKey=GBJVVSCPOBPEIT-UHFFFAOYSA-N

Data: 2 KI  9 IC50  5 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 50241089   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase C (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase C (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25.3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	693	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15.5	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	193	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.359	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase C (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aurora kinase C (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM50241089 (CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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