BDBM50241119 7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzooxazol-2-one::BIFEPRUNOX::CHEMBL218166

SMILES: O=c1[nH]c2cccc(N3CCN(Cc4cccc(c4)-c4ccccc4)CC3)c2o1

InChI Key: InChIKey=CYGODHVAJQTCBG-UHFFFAOYSA-N

Data: 13 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50241119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Human)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	324	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		7.19	-11.5	n/a	n/a	n/a	n/a	n/a	7.4	37
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D(2) dopamine receptor (Human)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		8.81	-11.0	n/a	n/a	n/a	n/a	n/a	7.4	25
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5-hydroxytryptamine receptor 1A (Human)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50241119 (CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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