BDBM50241313 (5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1,3-dienyl]thiophen-2(5H)-one::(R)-(+)-Thiolactomycin::(R)-4-Hydroxy-3,5-dimethyl-5-((E)-2-methyl-buta-1,3-dienyl)-5H-thiophen-2-one::(R,E)-4-hydroxy-3,5-dimethyl-5-(2-methylbuta-1,3-dienyl)thiophen-2(5H)-one::5R-Thiolactomycin::CHEMBL399043::TLM analog, 1

SMILES: CC1C(=O)S[C@](C)(\C=C(/C)C=C)C1=O

InChI Key: InChIKey=IKJRVRCIDNWYPZ-UHFFFAOYSA-N

Data: 2 KI  11 IC50  6 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50241313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-oxoacyl-[acyl-carrier-protein] synthase 2 (Staphylococcus aureus)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.07E+5	n/a	n/a	n/a	n/a	n/a
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Fatty acid synthase (Rat)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>9.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Fatty acid synthase (Human)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
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3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fatty acid synthase (Human)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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3-oxoacyl-[acyl-carrier-protein] synthase 1 (Escherichia coli (strain K12))	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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3-oxoacyl-[acyl-carrier-protein] synthase 2 (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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3-oxoacyl-[acyl-carrier-protein] synthase 3 (Escherichia coli)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.21E+5	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 1 (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.26E+5	n/a	n/a	n/a	8.5	n/a
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					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 2 (Staphylococcus aureus)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 2 (Staphylococcus aureus)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.07E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 2 (Staphylococcus aureus)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fatty acid synthase (Human)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Fatty acid synthase (Human)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
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DNA-(apurinic or apyrimidinic site) endonuclease (Human)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 1 (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	8.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 1 (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM50241313 ((R)-(+)-Thiolactomycin | (5R)-4-hydroxy-3,5-dimeth...) Show SMILES Show InChI	GoogleScholar	UniChem		1.75E+5	n/a	n/a	n/a	n/a	n/a	n/a	8.5	n/a
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					More data for this Ligand-Target Pair