BDBM50241453 1,3,6,7-tetrahydroxy-2,8-bis(3-methylbut-2-enyl)-9H-xanthen-9-one::CHEMBL260553::gamma-mangostin

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc2oc3cc(-[#8])c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c3c(=O)c2c1-[#8]

InChI Key: InChIKey=QAMMQIIXTAQRHX-UHFFFAOYSA-N

Data: 4 KI  15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50241453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable maltase-glucoamylase 2 (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
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Fatty acid synthase (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sialidase (Clostridium perfringens)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aromatase (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aromatase (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
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NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
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NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
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NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Transthyretin (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphoglycerate mutase 1 (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Oxidized purine nucleoside triphosphate hydrolase (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sialidase (Clostridium perfringens)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Probable maltase-glucoamylase 2 (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM50241453 (gamma-mangostin | 1,3,6,7-tetrahydroxy-2,8-bis(3-m...) Show SMILES Show InChI	GoogleScholar	UniChem		3.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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