BDBM50241727 (S)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid::1-Methyl-Tryptophan::1-methyltryptophan::CHEMBL504816::L-1-methyl-tryptophan

SMILES: Cn1cc(c2c1cccc2)C[C@@H](C(=O)O)N

InChI Key: InChIKey=ZADWXFSZEAPBJS-UHFFFAOYSA-N

Data: 12 KI  28 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 41 hits for monomerid = 50241727   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 2 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.99E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.85E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mouse)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Mouse)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.19E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 2 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 2 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 2 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		4.23E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		5.32E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 2 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 2 (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		4.25E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50241727 (L-1-methyl-tryptophan | (S)-2-amino-3-(1-methyl-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		8.10E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair