BDBM50242401 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile::A-769662::CHEMBL512504

SMILES: c1ccc(c(c1)c2ccc(cc2)c3csc4c3C(=C(C(=O)N4)C#N)O)O

InChI Key: InChIKey=CTESJDQKVOEUOY-UHFFFAOYSA-N

Data: 3 Kd  3 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50242401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-1 (Human)	BDBM50242401 (A-769662 | 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Human)	BDBM50242401 (A-769662 | 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-2/subunit gamma-1 (Human)	BDBM50242401 (A-769662 | 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Human)	BDBM50242401 (A-769662 | 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1 (Rat)	BDBM50242401 (A-769662 | 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	116	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Human)	BDBM50242401 (A-769662 | 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	487	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair