BDBM50242402 4-Hydroxynonenal::4-hydroxy-2-nonenal::CHEMBL454280

SMILES CCCCCC(O)\C=C\C=O

InChI Key InChIKey=JVJFIQYAHPMBBX-FNORWQNLSA-N

Data  4 EC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50242402   

TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Florence University

Curated by ChEMBL
LigandPNGBDBM50242402(4-Hydroxynonenal | 4-hydroxy-2-nonenal | CHEMBL454...)
Affinity DataEC50:  2.70E+4nMAssay Description:Agonist activity at rat TRPA1 channel expressed in tetracycline induced HEK293 cells assessed as increase in intracellular calciumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Florence University

Curated by ChEMBL
LigandPNGBDBM50242402(4-Hydroxynonenal | 4-hydroxy-2-nonenal | CHEMBL454...)
Affinity DataEC50:  1.99E+4nMAssay Description:Agonist activity at TRPA1 channel in rat DRG neurons assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Florence University

Curated by ChEMBL
LigandPNGBDBM50242402(4-Hydroxynonenal | 4-hydroxy-2-nonenal | CHEMBL454...)
Affinity DataEC50:  2.70E+4nMAssay Description:Agonist activity at rat TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Florence University

Curated by ChEMBL
LigandPNGBDBM50242402(4-Hydroxynonenal | 4-hydroxy-2-nonenal | CHEMBL454...)
Affinity DataEC50:  7.70E+4nMAssay Description:Activation of TRPA1 channel in rat dorsal root ganglion neurons assessed as increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed