BDBM50242645 CHEMBL486223::N,N-dimethyl-5-((7-phenyloctanamido)methyl)-2H-tetrazole-2-carboxamide

SMILES CN(C)C(=O)n1nnc(CNC(=O)CCCCCCCc2ccccc2)n1

InChI Key InChIKey=PPVBNTONKNSVRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242645   

TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50242645(CHEMBL486223 | N,N-dimethyl-5-((7-phenyloctanamido...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50242645(CHEMBL486223 | N,N-dimethyl-5-((7-phenyloctanamido...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed