BDBM50242788 2-((3,5-bis(trifluoromethyl)benzyl)(4-(4-methoxyphenylsulfonamido)phenyl)amino)-2-oxoacetic acid::CHEMBL459846

SMILES: COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)C(O)=O

InChI Key: InChIKey=MVHBPVBPUSMSRL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242788   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen activator inhibitor-1 (Homo sapiens (Human))	BDBM50242788 (2-((3,5-bis(trifluoromethyl)benzyl)(4-(4-methoxyph...) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)C(O)=O Show InChI InChI=1S/C24H18F6N2O6S/c1-38-19-6-8-20(9-7-19)39(36,37)31-17-2-4-18(5-3-17)32(21(33)22(34)35)13-14-10-15(23(25,26)27)12-16(11-14)24(28,29)30/h2-12,31H,13H2,1H3,(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Inhibition of human PAI1 by chromogenic assay				Eur J Med Chem 43: 880-4 (2008) Article DOI: 10.1016/j.ejmech.2007.05.011 BindingDB Entry DOI: 10.7270/Q25Q4VWX
					More data for this Ligand-Target Pair