BDBM50243258 (S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophen-2-yl)urea::CHEMBL487273

SMILES: c1ccc(cc1)c2cc(c(s2)NC(=O)N)C(=O)N[C@H]3CCCNC3

InChI Key: InChIKey=UXZRCIBKIDILEF-UHFFFAOYSA-N

Data: 7 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50243258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Human)	BDBM50243258 ((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50243258 ((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50243258 ((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50243258 ((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50243258 ((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2-associated protein 1 (Human)	BDBM50243258 ((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50243258 ((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50243258 ((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50243258 ((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50243258 ((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair