BDBM50243319 CHEMBL453582::isoindolin-2-yl((2S,4R)-4-(naphthalen-2-ylamino)pyrrolidin-2-yl)methanone

SMILES O=C([C@@H]1C[C@H](CN1)Nc1ccc2ccccc2c1)N1Cc2ccccc2C1

InChI Key InChIKey=WFOFPRCEEYVLCT-YADHBBJMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243319   

TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243319(CHEMBL453582 | isoindolin-2-yl((2S,4R)-4-(naphthal...)
Affinity DataIC50:  380nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243319(CHEMBL453582 | isoindolin-2-yl((2S,4R)-4-(naphthal...)
Affinity DataIC50:  2.65E+3nMAssay Description:Inhibition of DPP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243319(CHEMBL453582 | isoindolin-2-yl((2S,4R)-4-(naphthal...)
Affinity DataIC50:  290nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243319(CHEMBL453582 | isoindolin-2-yl((2S,4R)-4-(naphthal...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed