BDBM50243879 5-Hydroxy-4-(1H-indol-3-yl)-3-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one::CHEMBL505253

SMILES COc1cc(cc(OC)c1OC)C1=C(C(O)NC1=O)c1c[nH]c2ccccc12

InChI Key InChIKey=IINDUQOQNFCDNN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243879   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243879(5-Hydroxy-4-(1H-indol-3-yl)-3-(3,4,5-trimethoxyphe...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human recombinant VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243879(5-Hydroxy-4-(1H-indol-3-yl)-3-(3,4,5-trimethoxyphe...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human recombinant FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243879(5-Hydroxy-4-(1H-indol-3-yl)-3-(3,4,5-trimethoxyphe...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed