BDBM50243978 4-{1-[(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl]-1H-indol-3-yl}-3-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one::CHEMBL509635

SMILES COc1cc(cc(OC)c1OC)C1=C(CNC1=O)c1cn(CC2COC(C)(C)O2)c2ccccc12

InChI Key InChIKey=CCYHKZZXNPUQDU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243978   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243978(4-{1-[(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl]-1H-i...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human recombinant VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243978(4-{1-[(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl]-1H-i...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of human recombinant TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243978(4-{1-[(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl]-1H-i...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human recombinant SAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243978(4-{1-[(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl]-1H-i...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed