BDBM50243992 (trans)-4-methyl-1-(thiophen-2-yl)-3-aza-bicyclo[3.1.0]hexane::CHEMBL453576

SMILES C[C@H]1NC[C@]2(C[C@@H]12)c1cccs1

InChI Key InChIKey=BQORSRVGJSQEKY-WEDXCCLWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243992   

TargetTransporter(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243992((trans)-4-methyl-1-(thiophen-2-yl)-3-aza-bicyclo[3...)
Affinity DataIC50:  320nMAssay Description:Inhibition of norepinephrine uptake at NET in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243992((trans)-4-methyl-1-(thiophen-2-yl)-3-aza-bicyclo[3...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of dopamine uptake at cloned DAT in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243992((trans)-4-methyl-1-(thiophen-2-yl)-3-aza-bicyclo[3...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of serotonin uptake at SERT in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed