BDBM50244133 2-(4-tert-Butylphenyl)-4-(4-(2-(2-(trifluoromethyl)-1Hbenzo[d]imidazol-4-yloxy)ethyl)piperazin-1-yl)-1Hbenzo[d]imidazole::CHEMBL444509

SMILES CC(C)(C)c1ccc(cc1)-c1nc2c(cccc2[nH]1)N1CCN(CCOc2cccc3nc([nH]c23)C(F)(F)F)CC1

InChI Key InChIKey=UBUCIIFBJIRGAF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244133   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244133(2-(4-tert-Butylphenyl)-4-(4-(2-(2-(trifluoromethyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244133(2-(4-tert-Butylphenyl)-4-(4-(2-(2-(trifluoromethyl...)
Affinity DataIC50:  50nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244133(2-(4-tert-Butylphenyl)-4-(4-(2-(2-(trifluoromethyl...)
Affinity DataIC50:  710nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed