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BDBM50244136 1-(cyclopropylmethyl)-2-((6-ethoxypyridin-3-yl)methyl)-N,N-diethyl-1H-benzo[d]imidazole-5-carboxamide::CHEMBL461920

SMILES: CCOc1ccc(Cc2nc3cc(ccc3n2CC2CC2)C(=O)N(CC)CC)cn1

InChI Key: InChIKey=UOHNZPHAELANCA-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244136   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50244136
PNG
(1-(cyclopropylmethyl)-2-((6-ethoxypyridin-3-yl)met...)
Show SMILES CCOc1ccc(Cc2nc3cc(ccc3n2CC2CC2)C(=O)N(CC)CC)cn1
Show InChI InChI=1S/C24H30N4O2/c1-4-27(5-2)24(29)19-10-11-21-20(14-19)26-22(28(21)16-17-7-8-17)13-18-9-12-23(25-15-18)30-6-3/h9-12,14-15,17H,4-8,13,16H2,1-3H3
PDB

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KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
133n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montréal

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 18: 3695-700 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.073
BindingDB Entry DOI: 10.7270/Q2J38SBN
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50244136
PNG
(1-(cyclopropylmethyl)-2-((6-ethoxypyridin-3-yl)met...)
Show SMILES CCOc1ccc(Cc2nc3cc(ccc3n2CC2CC2)C(=O)N(CC)CC)cn1
Show InChI InChI=1S/C24H30N4O2/c1-4-27(5-2)24(29)19-10-11-21-20(14-19)26-22(28(21)16-17-7-8-17)13-18-9-12-23(25-15-18)30-6-3/h9-12,14-15,17H,4-8,13,16H2,1-3H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>5.00E+3n/an/an/an/an/an/an/an/a



AstraZeneca R&D Montréal

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 18: 3695-700 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.073
BindingDB Entry DOI: 10.7270/Q2J38SBN
More data for this
Ligand-Target Pair