BDBM50244449 (E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)methylene)-5-oxo-tetrahydrofuran-2-yl)methyl 2-propylpentanoate::CHEMBL519741

SMILES: CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1

InChI Key: InChIKey=SIWILCBNYOGJQH-UHFFFAOYSA-N

Data: 12 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50244449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ras guanyl-releasing protein 3 (Human)	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Human)	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Human)	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Human)	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Human)	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair