BDBM50244787 (R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phenylamino]-9-isopropylpurine::CHEMBL215919

SMILES: CC[C@H](CO)Nc1nc(Nc2cccc(c2)-c2ccccn2)c2ncn(C(C)C)c2n1

InChI Key: InChIKey=LWANFAFTTOKZAX-UHFFFAOYSA-N

Data: 15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50244787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta/[Tau protein] kinase (Pig)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase 5 activator 1 (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	215	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-T1/Cyclin-dependent kinase 9 (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	822	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Casein kinase I isoform alpha (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase 5 (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Glycogen synthase kinase-3 beta (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Casein kinase I isoform alpha (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM50244787 ((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair