BDBM50245024 2-hydroxy-5-((4-oxo-2-thioxo-3-(4-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid::CHEMBL488016

SMILES OC(=O)c1cc(\C=C2/SC(=S)N(C2=O)c2ccc(cc2)C(F)(F)F)ccc1O

InChI Key InChIKey=DMIWVWYKHHMBIN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245024   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50245024(2-hydroxy-5-((4-oxo-2-thioxo-3-(4-(trifluoromethyl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human wild type CFTR expressed in rat FRT cells assessed as chloride current by short-circuit current measurementsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed