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BDBM50245087 CHEMBL508165::rac-(E/Z)-Diphenyl-acetic acid 2-hydroxymethyl-5-oxo-4-[1-(4'-trifluoromethyl-biphenyl-4-yl)-methylidene]-tetrahydro-furan-2-ylmethyl ester

SMILES: OCC1(COC(=O)C(c2ccccc2)c2ccccc2)C\C(=C\c2ccc(cc2)-c2ccc(cc2)C(F)(F)F)C(=O)O1

InChI Key: InChIKey=KIHLNCRBATYBFY-USHMODERNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245087   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C


(MOUSE)
BDBM50245087
PNG
(CHEMBL508165 | rac-(E/Z)-Diphenyl-acetic acid 2-hy...)
Show SMILES OCC1(COC(=O)C(c2ccccc2)c2ccccc2)C\C(=C\c2ccc(cc2)-c2ccc(cc2)C(F)(F)F)C(=O)O1
Show InChI InChI=1/C34H27F3O5/c35-34(36,37)29-17-15-25(16-18-29)24-13-11-23(12-14-24)19-28-20-33(21-38,42-31(28)39)22-41-32(40)30(26-7-3-1-4-8-26)27-9-5-2-6-10-27/h1-19,30,38H,20-22H2/b28-19-
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
111n/an/an/an/an/an/an/an/a



National Cancer Institute-Frederick

Curated by ChEMBL


Assay Description
Displacement of [3H]PDBu form mouse PKCalpha by scintillation counting


J Med Chem 51: 5198-220 (2008)


Article DOI: 10.1021/jm8001907
BindingDB Entry DOI: 10.7270/Q2G44Q4B
More data for this
Ligand-Target Pair