BDBM50245769 1-(2-chloro-4-(trifluoromethyl)phenyl)-3-(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-1H-indazol-3-yl)urea::CHEMBL452088

SMILES COc1cc2nccc(Oc3ccc4c(NC(=O)Nc5ccc(cc5Cl)C(F)(F)F)nn(C)c4c3)c2cc1OC

InChI Key InChIKey=XZVLDNHMTPTVMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245769   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245769(1-(2-chloro-4-(trifluoromethyl)phenyl)-3-(6-(6,7-d...)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed