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BDBM50245930 CHEMBL461151::N-(2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-yl)furan-3-carboxamide

SMILES: O=C(Nc1nc2ccccc2c2cn(nc12)-c1ccccc1)c1ccoc1

InChI Key: InChIKey=FHZBUNWPMXSOKQ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245930   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50245930
PNG
(CHEMBL461151 | N-(2-phenyl-2H-pyrazolo[3,4-c]quino...)
Show SMILES O=C(Nc1nc2ccccc2c2cn(nc12)-c1ccccc1)c1ccoc1
Show InChI InChI=1S/C21H14N4O2/c26-21(14-10-11-27-13-14)23-20-19-17(16-8-4-5-9-18(16)22-20)12-25(24-19)15-6-2-1-3-7-15/h1-13H,(H,22,23,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
50n/an/an/an/an/an/an/an/a



Università di Firenze

Curated by ChEMBL


Assay Description
Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells by scintillation counting


Bioorg Med Chem 17: 401-10 (2008)


Article DOI: 10.1016/j.bmc.2008.10.018
BindingDB Entry DOI: 10.7270/Q21N810X
More data for this
Ligand-Target Pair