BDBM50245939 1-(5-(3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl)thiophen-2-yl)-2,2,2-trifluoroethanone::CHEMBL460088

SMILES Fc1ccc(-c2noc(n2)-c2ccc(s2)C(=O)C(F)(F)F)c(F)c1

InChI Key InChIKey=ZODJGPAXHPYDLJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50245939   

TargetHistone deacetylase 4(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245939(1-(5-(3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl)...)
Affinity DataIC50: 120nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245939(1-(5-(3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl)...)
Affinity DataIC50: 580nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245939(1-(5-(3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245939(1-(5-(3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl)...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed