BDBM50245941 1-(5-(3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl)thiophen-2-yl)-2,2,2-trifluoroethanone::CHEMBL461142

SMILES CC(C)(C)c1ccc(cc1)-c1noc(n1)-c1ccc(s1)C(=O)C(F)(F)F

InChI Key InChIKey=OYODCWRDYHHIFP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50245941   

TargetHistone deacetylase 3(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245941(1-(5-(3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245941(1-(5-(3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl)...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245941(1-(5-(3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl)...)
Affinity DataIC50: 3.54E+3nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245941(1-(5-(3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl)...)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed