BDBM50245949 2-(butylthio)-4-(dimethylamino)-8-(4-fluorobenzyl)pteridine-6,7(5H,8H)-dione::CHEMBL517716

SMILES CCCCSc1nc(N(C)C)c2[nH]c(=O)c(=O)n(Cc3ccc(F)cc3)c2n1

InChI Key InChIKey=UCLRXYWILWWQOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245949   

TargetGlutamate racemase(Enterococcus faecalis)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50245949(2-(butylthio)-4-(dimethylamino)-8-(4-fluorobenzyl)...)
Affinity DataIC50:  1.10E+3nMpH: 8.0Assay Description:Inhibition of Enterococcus faecalis murI assessed as effect on conversion of D-glutamate to L-glutamate at pH 8.0 by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed