BDBM50246240 2-Methyl-3-(4-{[3-(1-piperidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone::2-methyl-3-(4-(3-(piperidin-1-yl)propoxy)phenyl)quinazolin-4(3H)-one::CHEMBL487063

SMILES Cc1nc2ccccc2c(=O)n1-c1ccc(OCCCN2CCCCC2)cc1

InChI Key InChIKey=SNAHQQBXZGIQLV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50246240   

TargetHistamine H3 receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246240(2-Methyl-3-(4-{[3-(1-piperidinyl)propyl]oxy}phenyl...)
Affinity DataIC50:  3.10nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246240(2-Methyl-3-(4-{[3-(1-piperidinyl)propyl]oxy}phenyl...)
Affinity DataIC50:  8.60E+3nMAssay Description:Displacement of [35S]N-[(4R)-1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246240(2-Methyl-3-(4-{[3-(1-piperidinyl)propyl]oxy}phenyl...)
Affinity DataIC50:  6.50E+3nMAssay Description:Displacement of [3H]prazosin from human adrenergic alpha1A receptor expressed in LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246240(2-Methyl-3-(4-{[3-(1-piperidinyl)propyl]oxy}phenyl...)
Affinity DataIC50:  7.90E+3nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50246240(2-Methyl-3-(4-{[3-(1-piperidinyl)propyl]oxy}phenyl...)
Affinity DataIC50:  3.10nMAssay Description:Inverse agonist activity at human histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed