BDBM50246327 4-(4-((1R,2R)-2-(dimethylamino)cyclopentylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-N-methylbenzenesulfonamide::4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide::CHEMBL509485
SMILES CNS(=O)(=O)c1ccc(Nc2ncc(c(N[C@@H]3CCC[C@H]3N(C)C)n2)C(F)(F)F)cc1
InChI Key InChIKey=CAUFYHKGKDJMQG-HZPDHXFCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50246327
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of GST-tagged FAK (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 154nMAssay Description:Inhibition of GST-tagged pyk2 (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of purified activated FAK kinase domain (410-689) using ATP and Glu and Tyr random peptide polymer substrate by fluorescence polarization ...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of PYK2 assessed as reduction in peptide substrate phosphoryltion by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of PYK2 by PYK2-LI-COR cellular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of GST-tagged FAK (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylation by fluorescence polarization assayMore data for this Ligand-Target Pair