BDBM50246380 2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-methoxy-3-methylquinazolin-4(3H)-one::CHEMBL453892

SMILES: COc1cccc2c1nc(-c1ccc(OC3CCN(CC3)C3CCC3)cc1)n(C)c2=O

InChI Key: InChIKey=MUZZBBKURZZINE-UHFFFAOYSA-N

Data: 1 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50246380   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Human)	BDBM50246380 (2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50246380 (2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM50246380 (2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50246380 (2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM50246380 (2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		0.156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair