BDBM50246461 4-(7-fluoro-2-(6-methoxy-3,4-dihydro-2H-chromen-3-yl)-3H-benzo[d]imidazol-5-yl)pyrimidin-2-amine::CHEMBL452598

SMILES: COc1ccc2OCC(Cc2c1)c1nc2cc(cc(F)c2[nH]1)-c1ccnc(N)n1

InChI Key: InChIKey=LGNRWEUQQPIDQM-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50246461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Human)	BDBM50246461 (4-(7-fluoro-2-(6-methoxy-3,4-dihydro-2H-chromen-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<6	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 2 (Human)	BDBM50246461 (4-(7-fluoro-2-(6-methoxy-3,4-dihydro-2H-chromen-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM50246461 (4-(7-fluoro-2-(6-methoxy-3,4-dihydro-2H-chromen-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50246461 (4-(7-fluoro-2-(6-methoxy-3,4-dihydro-2H-chromen-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM50246461 (4-(7-fluoro-2-(6-methoxy-3,4-dihydro-2H-chromen-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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