BDBM50246599 CHEMBL471537::N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphenyl)ethylcarbamoyl]methyl}-D-valinehydroxamic Acid

SMILES CC(C)[C@@H](N(CC(=O)NCCc1ccc(cc1)S(N)(=O)=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO

InChI Key InChIKey=GSWRTFGMHRKLKT-AREMUKBSSA-N

Data  3 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50246599   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Affinity DataKi:  730nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of human recombinant MMP2 transfected in mouse melanoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Affinity DataIC50:  55nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed