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BDBM50246724 CHEMBL4085451

SMILES: [I-].COc1cccc2CC(CCc12)[N+](C)(C)C

InChI Key: InChIKey=WMTOMXCTHCDJRK-UHFFFAOYSA-M

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50246724   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50246724
PNG
(CHEMBL4085451)
Show SMILES [I-].COc1cccc2CC(CCc12)[N+](C)(C)C
Show InChI InChI=1S/C14H22NO.HI/c1-15(2,3)12-8-9-13-11(10-12)6-5-7-14(13)16-4;/h5-7,12H,8-10H2,1-4H3;1H/q+1;/p-1
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Article
PubMed
2.50E+3n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopolamine bromide from human recombinant muscarinic M1 receptor expressed in HEK293T cell membranes after 1 hr by liqu...


J Med Chem 60: 9239-9250 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01113
BindingDB Entry DOI: 10.7270/Q2445PW2
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50246724
PNG
(CHEMBL4085451)
Show SMILES [I-].COc1cccc2CC(CCc12)[N+](C)(C)C
Show InChI InChI=1S/C14H22NO.HI/c1-15(2,3)12-8-9-13-11(10-12)6-5-7-14(13)16-4;/h5-7,12H,8-10H2,1-4H3;1H/q+1;/p-1
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KEGG

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antibodypedia
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PC sid
UniChem

Patents


Similars

Article
PubMed
4.00E+3n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopolamine bromide from human recombinant muscarinic M3 receptor expressed in HEK293T cell membranes after 1 hr by liqu...


J Med Chem 60: 9239-9250 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01113
BindingDB Entry DOI: 10.7270/Q2445PW2
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2 and M4


(Homo sapiens (Human))
BDBM50246724
PNG
(CHEMBL4085451)
Show SMILES [I-].COc1cccc2CC(CCc12)[N+](C)(C)C
Show InChI InChI=1S/C14H22NO.HI/c1-15(2,3)12-8-9-13-11(10-12)6-5-7-14(13)16-4;/h5-7,12H,8-10H2,1-4H3;1H/q+1;/p-1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4.40E+3n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopolamine bromide from human recombinant muscarinic M2 receptor expressed in HEK293T cell membranes after 1 hr by liqu...


J Med Chem 60: 9239-9250 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01113
BindingDB Entry DOI: 10.7270/Q2445PW2
More data for this
Ligand-Target Pair