BDBM50246823 CHEMBL4071277

SMILES OC[C@H]1CNC(=N)N1CCc1cccnc1

InChI Key InChIKey=YPNOTFAUEIKCKT-SNVBAGLBSA-N

Data  5 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50246823   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50246823(CHEMBL4071277)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK cell membranes after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50246823(CHEMBL4071277)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta2 nAChR expressed in HEK cell membranes after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50246823(CHEMBL4071277)
Affinity DataKi:  184nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta4 nAChR expressed in HEK cell membranes after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-5/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50246823(CHEMBL4071277)
Affinity DataKi:  957nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4alpha5 nAChR expressed in HEK cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50246823(CHEMBL4071277)
Affinity DataKi:  964nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK cell membranes after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50246823(CHEMBL4071277)
Affinity DataEC50:  2.54E+3nMAssay Description:Agonist activity at rat alpha3beta4 nAChR expressed in HEK cells assessed as induction of Ca2+ fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50246823(CHEMBL4071277)
Affinity DataIC50:  2.72E+3nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK cells assessed as inhibition of Ca2+ fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50246823(CHEMBL4071277)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at rat alpha4beta2 nAChR expressed in HEK cells assessed as inhibition of epibatidine-induced membrane potential preincubated for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed