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BDBM50246949 4-[(E)-2-(3-Carboxy-4-hydroxyphenyl)vinyl]-2-hydroxybenzoic acid::CHEMBL453874

SMILES: OC(=O)c1ccc(\C=C\c2ccc(O)c(c2)C(O)=O)cc1O

InChI Key: InChIKey=ADOBRESLNOQZTQ-OWOJBTEDSA-N

Data: 3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50246949   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50246949
PNG
(4-[(E)-2-(3-Carboxy-4-hydroxyphenyl)vinyl]-2-hydro...)
Show SMILES OC(=O)c1ccc(\C=C\c2ccc(O)c(c2)C(O)=O)cc1O
Show InChI InChI=1S/C16H12O6/c17-13-6-4-9(7-12(13)16(21)22)1-2-10-3-5-11(15(19)20)14(18)8-10/h1-8,17-18H,(H,19,20)(H,21,22)/b2-1+
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.20E+4n/an/an/an/an/an/a



Inha University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B (unknown origin)


Bioorg Med Chem 16: 8643-52 (2008)


Article DOI: 10.1016/j.bmc.2008.07.090
BindingDB Entry DOI: 10.7270/Q2KP820N
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1C


(Homo sapiens (Human))
BDBM50246949
PNG
(4-[(E)-2-(3-Carboxy-4-hydroxyphenyl)vinyl]-2-hydro...)
Show SMILES OC(=O)c1ccc(\C=C\c2ccc(O)c(c2)C(O)=O)cc1O
Show InChI InChI=1S/C16H12O6/c17-13-6-4-9(7-12(13)16(21)22)1-2-10-3-5-11(15(19)20)14(18)8-10/h1-8,17-18H,(H,19,20)(H,21,22)/b2-1+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.31E+5n/an/an/an/an/an/a



Inha University

Curated by ChEMBL


Assay Description
Inhibition of PTP SHP1 (unknown origin)


Bioorg Med Chem 16: 8643-52 (2008)


Article DOI: 10.1016/j.bmc.2008.07.090
BindingDB Entry DOI: 10.7270/Q2KP820N
More data for this
Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2


(Homo sapiens (Human))
BDBM50246949
PNG
(4-[(E)-2-(3-Carboxy-4-hydroxyphenyl)vinyl]-2-hydro...)
Show SMILES OC(=O)c1ccc(\C=C\c2ccc(O)c(c2)C(O)=O)cc1O
Show InChI InChI=1S/C16H12O6/c17-13-6-4-9(7-12(13)16(21)22)1-2-10-3-5-11(15(19)20)14(18)8-10/h1-8,17-18H,(H,19,20)(H,21,22)/b2-1+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.67E+5n/an/an/an/an/an/a



Inha University

Curated by ChEMBL


Assay Description
Inhibition of TC-PTP (unknown origin)


Bioorg Med Chem 16: 8643-52 (2008)


Article DOI: 10.1016/j.bmc.2008.07.090
BindingDB Entry DOI: 10.7270/Q2KP820N
More data for this
Ligand-Target Pair