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BDBM50247019 1-(4-[N-(2-Methoxy-2-oxoethylcarbamoyl]aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine::CHEMBL516788

SMILES: COC(=O)CNC(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12

InChI Key: InChIKey=BORVLTYUPGZZMD-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247019   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50247019
PNG
(1-(4-[N-(2-Methoxy-2-oxoethylcarbamoyl]aminomethyl...)
Show SMILES COC(=O)CNC(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12
Show InChI InChI=1S/C23H27N3O4/c1-16-13-18(10-11-19(16)14-24-23(29)25-15-21(27)30-2)22(28)26-12-6-5-8-17-7-3-4-9-20(17)26/h3-4,7,9-11,13H,5-6,8,12,14-15H2,1-2H3,(H2,24,25,29)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 37n/an/an/an/a



Vantia Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...


J Med Chem 51: 8124-34 (2008)


Article DOI: 10.1021/jm8008162
BindingDB Entry DOI: 10.7270/Q28W3D6V
More data for this
Ligand-Target Pair