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BDBM50247613 (3S,4R)-4-(5-Fluoro-benzothiazol-2-ylamino)-3-hydroxy-2,2-dimethyl-chroman-6-carbonitrile::CHEMBL490883

InChI string: InChI=1S/C19H16FN3O2S/c1-19(2)17(24)16(12-7-10(9-21)3-6-15(12)25-19)26-18-22-13-5-4-11(20)8-14(13)23-18/h3-8,16-17,24H,1-2H3,(H,22,23)/t16-,17+/m1/s1

SMILES: CC1(C)Oc2ccc(cc2[C@@H](Sc2nc3ccc(F)cc3[nH]2)[C@@H]1O)C#N

InChI Key: InChIKey=UGDZHIHTHCQYKA-SJORKVTESA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247613   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247613
PNG
((3S,4R)-4-(5-Fluoro-benzothiazol-2-ylamino)-3-hydr...)
Show SMILES CC1(C)Oc2ccc(cc2[C@@H](Sc2nc3ccc(F)cc3[nH]2)[C@@H]1O)C#N
Show InChI InChI=1S/C19H16FN3O2S/c1-19(2)17(24)16(12-7-10(9-21)3-6-15(12)25-19)26-18-22-13-5-4-11(20)8-14(13)23-18/h3-8,16-17,24H,1-2H3,(H,22,23)/t16-,17+/m1/s1
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AffyNet 
Article
PubMed
n/an/an/an/a 8.44E+3n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Citation and Details
More data for this
Ligand-Target Pair