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BDBM50247681 (+/-)-4-chlorophenyl 6-cyano-3-hydroxy-2,2-dimethylchroman-4-ylcarbamate::CHEMBL508050

InChI string: InChI=1S/C19H17ClN2O3/c1-19(2)17(23)16(14-9-11(10-21)3-8-15(14)25-19)22-18(24)12-4-6-13(20)7-5-12/h3-9,16-17,23H,1-2H3,(H,22,24)

SMILES: CC1(C)Oc2ccc(cc2C(NC(=O)c2ccc(Cl)cc2)C1O)C#N

InChI Key: InChIKey=ZWWROLFBGFHLTP-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247681   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sulfonylurea receptor 2, Kir6.2


(Homo sapiens)
BDBM50247681
PNG
((+/-)-4-chlorophenyl 6-cyano-3-hydroxy-2,2-dimethy...)
Show SMILES CC1(C)Oc2ccc(cc2C(NC(=O)c2ccc(Cl)cc2)C1O)C#N
Show InChI InChI=1S/C19H17ClN2O3/c1-19(2)17(23)16(14-9-11(10-21)3-8-15(14)25-19)22-18(24)12-4-6-13(20)7-5-12/h3-9,16-17,23H,1-2H3,(H,22,24)
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AffyNet 
Article
PubMed
n/an/an/an/a 780n/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR


Citation and Details
More data for this
Ligand-Target Pair