BDBM50247980 1-(2-((R)-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-3-methylphenyl)-5-methyl-N,N-diphenyl-1H-pyrazole-3-carboxamide::CHEMBL503783

SMILES Cc1cc(nn1-c1cccc(C)c1C(=O)N1Cc2ccccc2C[C@@H]1CO)C(=O)N(c1ccccc1)c1ccccc1

InChI Key InChIKey=PKQWGZFPCGTPLJ-SSEXGKCCSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50247980   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50247980(1-(2-((R)-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoq...)
Affinity DataIC50:  390nMAssay Description:Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50247980(1-(2-((R)-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoq...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50247980(1-(2-((R)-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoq...)
Affinity DataIC50:  390nMAssay Description:Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed