BDBM50248362 Adcortyl::Adcortyl In Orabase::Allernaze::Aristocort::Aristocort A::Aristogel::Audicort::Aureocort::Azmacort::CHEBI:71418::Flutex::Gppe Ear Dps Cap::Gppe Ear Oint::Kenacort::Kenacourt::Kenalog::Kenalog In Orabase::Kenalog-10::Kenalog-40::Kenalog-H::Nasacort::Nasacort Aq::Nasacort Hfa::Nasacort allergy 24 hour::Nystadermal::Oracort::Oralone::Pevaryl T.C.::Remiderm::Remotic::Silderm::Tri-Adcortyl::Tri-Nasal::Triacet::Triacort::Triamcinolone Acetonide::Triamcinolone Acetonide In Absorbase::Triatex::Triderm::Triesence::Trivaris::Trymex::Vetalog::Zilretta

SMILES C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)CCC5=CC(=O)C=C[C@@]53C)F)O

InChI Key InChIKey=YNDXUCZADRHECN-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248362   

LigandPNGBDBM50248362(CHEBI:71418 | Adcortyl | Adcortyl In Orabase | All...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50248362(CHEBI:71418 | Adcortyl | Adcortyl In Orabase | All...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50248362(CHEBI:71418 | Adcortyl | Adcortyl In Orabase | All...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50248362(CHEBI:71418 | Adcortyl | Adcortyl In Orabase | All...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed