BDBM50248392 3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-3-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide::CHEMBL521777

SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(F)c3)cccc12

InChI Key InChIKey=KRIJDZSSADICAX-VMPITWQZSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50248392   

TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248392(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50:  1.37E+3nMAssay Description:Displacement of radioligand from EP1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248392(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of radioligand from EP2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248392(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50:  53.9nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248392(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50:  2.23E+3nMAssay Description:Displacement of radioligand from FP receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248392(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50:  6.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248392(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of radioligand from EP4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed