BDBM50248580 6-(4-carbamoylpiperidin-1-yl)-5-chloro-N-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-yl)nicotinamide::CHEMBL462874

SMILES NC(=O)C1CCN(CC1)c1ncc(cc1Cl)C(=O)Nc1nc(cs1)-c1cccc(c1F)C(F)(F)F

InChI Key InChIKey=RDTWLEBCFLFHPB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248580   

TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248580(6-(4-carbamoylpiperidin-1-yl)-5-chloro-N-(4-(2-flu...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed