BDBM50248586 2-(1-(4-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N-(pyridin-4-ylmethyl)aniline::CHEMBL461392

SMILES CC(C)(C)c1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1

InChI Key InChIKey=AJEMKTGHPQLPSM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50248586   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50248586(2-(1-(4-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)
Affinity DataIC50:  610nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50248586(2-(1-(4-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50248586(2-(1-(4-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)
Affinity DataIC50:  530nMAssay Description:Inhibition of VEGFR1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed