BDBM50249154 (S)-2-amino-3-(4-(biphenyl-4-ylmethoxy)phenylamino)-2-methyl-3-oxopropyl dihydrogen phosphate::CHEMBL473563
SMILES C[C@](N)(COP(O)(O)=O)C(=O)Nc1ccc(OCc2ccc(cc2)-c2ccccc2)cc1
InChI Key InChIKey=WJTKHEJZIPMAKN-QHCPKHFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50249154
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 21.1nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P3 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 44.1nMAssay Description:Agonist activity at human S1P1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.15nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 104nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P5 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair