BDBM50249195 8,15-dimethyl-N-(1,3,4-thiadiazol-2-yl)tetracyclo[6.6.2.0^{2,7}.0^{9,14}]hexadeca-2,4,6,9(14),10,12-hexaene-15-carboxamide::CHEMBL514630
SMILES CC1(CC2(C)c3ccccc3C1c1ccccc21)C(=O)Nc1nncs1
InChI Key InChIKey=ICFLHQGITDWVMH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50249195
Affinity DataKi: 1.30nMAssay Description:Displacement of FITC-dexamethasone from human recombinant glucocorticoid receptor alpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of FITC-dexamethasone from human recombinant glucocorticoid receptor alpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of radioligand from progesterone receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of radioligand from estrogen receptor alpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.30E+3nMAssay Description:Displacement of radioligand from androgen receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GR ligand binding domain expressed in human NP1 cells assessed as glucocorticoid response element transactivation by GAL4 lucifer...More data for this Ligand-Target Pair
Affinity DataEC50: 111nMAssay Description:Agonist activity at GR ligand binding domain expressed in human NP1 cells assessed as glucocorticoid response element transactivation by GAL4 lucifer...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GR ligand binding domain expressed in human NP1 cells assessed as glucocorticoid response element transactivation by GAL4 lucifer...More data for this Ligand-Target Pair
Affinity DataEC50: 8.30nMAssay Description:Transrepression activity at GR in IL-1-beta-stimulated human A549 cells assessed as inhibition of NF-kappaB-dependent E-selectin transcription by luc...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Transrepression activity at GR in IL-1-beta-stimulated human A549 cells assessed as inhibition of NF-kappaB-dependent E-selectin transcription by luc...More data for this Ligand-Target Pair
Affinity DataEC50: 11.4nMAssay Description:Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...More data for this Ligand-Target Pair
Affinity DataEC50: 16.9nMAssay Description:Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...More data for this Ligand-Target Pair
Affinity DataEC50: 16.9nMAssay Description:Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Transrepression activity at GR in IL-1-beta-stimulated human A549 cells assessed as inhibition of NF-kappaB-dependent E-selectin transcription by luc...More data for this Ligand-Target Pair